A more thorough explanation:

The Code of Federal Regulations (CFR) is a collection of rules and regulations created by the federal government's agencies and executive departments. It is published annually by the Office of the Federal Register and the Government Publishing Office. The CFR is a codification of the federal government's rules and regulations published in the Federal Register.

The CFR is different from the Federal Register because it only contains the final and effective rules of Federal agencies and any related official interpretations of the rules. It does not contain preambles, proposed rules, notices, or general policy statements found in the Federal Register.

The CFR is divided into 50 titles, each covering a specific subject area. Each agency is assigned chapters within the titles. The standard organization of a title consists of chapters, subchapters, parts, sections, and paragraphs.

• Title 21: Food and Drugs
• Title 29: Labor
• Title 40: Protection of Environment

These examples illustrate the subject areas covered by the CFR. Title 21 covers rules and regulations related to food and drugs, Title 29 covers labor-related rules and regulations, and Title 40 covers rules and regulations related to the protection of the environment.

The CFR reflects the tenet that the federal government must follow an open public process when rulemaking. The United States Constitution permits federal agencies to promulgate rules to enable Congress’ legislation. This rulemaking process is governed by the Administrative Procedure Act. Proposed rules must be first published in a Notice of Proposed Rulemaking. This notice allows the public to comment and participate in the rulemaking process before the final rule is adopted and published. A rule becomes final when it is published in the Federal Register.